scATAC-seq pipeline mapping mucosal immunity and host-microbe crosstalk. Profiles physical chromatin accessibility of Trm cells (Itgae/CD103) and Secretory IgA Plasma cells (Igj) to decode intestinal defense mechanisms.

A computational metataxonomics pipeline for 16S rRNA-seq, quantifying mucosal dysbiosis, differential microbial abundance, and co-occurrence network topologies to identify keystone taxa in Crohn's Disease.