A toolkit developed to predict and analyze PROTAC-mediated ternary complexes using AlphaFold3 and Boltz-1.
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Updated
Jul 17, 2025 - Python
A toolkit developed to predict and analyze PROTAC-mediated ternary complexes using AlphaFold3 and Boltz-1.
PROTAC-Splitter is a machine learning framework designed for automated annotation of PROTAC substructures.
Predicting PROTAC protein degradation activity via machine learning.
Dated, falsifiable biotech investment predictions in targeted protein degradation — published before the event, scored after, misses included. Full methodology, rNPV models, and the prediction log.
Kymera Therapeutics is a clinical-stage biopharmaceutical company headquartered at 500 North Beacon Street in Watertown, Massachusetts, pioneering targeted protein degradation as a way to build oral small-molecule medicines against targets that conventional inhibitors cannot reach.
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