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This project, undertaken within LifeArc, focuses on developing and optimizing an in vitro model system of human sensory neurons. The primary goal is to create a reliable and reproducible platform for testing novel analgesic compounds by directly converting human skin fibroblasts into functional sensory neurons.
Relevant material utilised in support of the Davidson, Simeone, and Jansen et al. 2026 Manuscipt. Spatial analysis of relevant fibroblast populations with reference to vasculature within and across tissue compartments