What you need to process the Quarterly DepMap-Omics releases from Terra

Cancer Dependency Map package

CanDI - A global cancer data integrator

An integrative resource for deubiquitinating enzymes (DUBs) served at https://labsyspharm.github.io/dubportal

Package to predict dependencies between cell lines and genes using Network Representation Learning (NRL) based Link Prediction

DeepVul: A Multi-Task Transformer Model for Joint Prediction of Gene Essentiality and Drug Response

Digital patient generation and drug response prediction via TCGA-DepMap integration — CVAE virtual patients, multi-level similarity scoring, 578-compound drug profiling

Interactive web viewer for TF ChIP-seq binding programs at canonical protein-coding TSSs (Ensembl GRCh38.114). Streamlit + Plotly + DuckDB; ~1,300 TFs × ~19,700 TSSs; NMF programs/archetypes, GTEx + DepMap overlays, atlas-wide TF×TF network.

Data from the Broad's Project Achilles synthetic-lethal screen ready for use in R.

A functional genomics framework for classifying homologous recombination deficiency and mapping PARP inhibitor sensitivity across DepMap cancer cell lines.

DepMap-based FAM50A dependency analysis in colorectal cancer with TCGA projection and CRISPR knockdown simulation.

虚拟小鼠 vmouse · IGFBP4 基因扰动数据包:LINCS/DepMap/IMPC/STRING 等真实公开数据检索+富集(非预测)

Interactive comparison of gene expression across 13 prostate-cancer cell lines (DepMap Public 26Q1): volcano plot, differential-gene table, and per-gene profiles. Live: https://yangcui0612.github.io/prostate-cell-line-expression/

Using MetMap500, we identified a 13-gene lung cancer metastasis signature linked to metastatic potential, poor prognosis, and broad drug resistance. The signature outperformed prior gene sets and prioritized crizotinib through transcriptomic and network-level associations.