Skip to content
View engavilane's full-sized avatar

Block or report engavilane

Block user

Prevent this user from interacting with your repositories and sending you notifications. Learn more about blocking users.

You must be logged in to block users.

Maximum 250 characters. Please donโ€™t include any personal information such as legal names or email addresses. Markdown is supported. This note will only be visible to you.
Report abuse

Contact GitHub support about this userโ€™s behavior. Learn more about reporting abuse.

Report abuse
engavilane/README.md

๐Ÿ‘‹ Hi there, Iโ€™m Enya

๐ŸŽ“ MSc Bioinformatics student at Universitรฉ Clermont Auvergne (France)
๐Ÿ’ป Exploring the crossroads of AI, Computational Biology, and Structural Bioinformatics
๐Ÿงฌ Passionate about understanding life through data and algorithms


๐ŸŒŸ About Me

Iโ€™m currently pursuing a Masterโ€™s degree in Bioinformatics, funded by the Excellence Scholarship in Artificial Intelligence (Cluster MIAI 2025โ€“2026).
My goal is to combine deep learning and molecular biology to improve drug discovery and protein modeling.

I love learning new technologies, analyzing biological data, and finding creative ways to represent complex biological systems.


๐Ÿง  Technical Skills

๐Ÿ’ป Programming

Python R Shell SQL

๐Ÿ“Š Data Science

  • Machine Learning (classification, clustering, CNNs, transformers)
  • Data preprocessing, feature engineering & model evaluation

๐Ÿงซ Bioinformatics

  • Sequence analysis (FASTA/FASTQ, BLAST, differential expression)
  • Protein structure prediction with AlphaFold, ESMFold
  • Genomics & transcriptomics pipelines
  • Databases: UniProt, PDB, NCBI, ChEMBL, Tox21, Ensembl, Bioconductor
  • Molecular docking & virtual screening (AutoDock Vina, Meeko)
  • Cheminformatics & ADME filtering (RDKit, Morgan fingerprints)
  • Structure-based ML for drug discovery (scikit-learn)
  • PDB/PubChem API automation (Python)

โš™๏ธ Tools & Environments

Linux Git Docker Jupyter VSCode


๐ŸŽ“ Education

๐ŸŽ“ MSc in Bioinformatics (2024โ€“2026) โ€” Universitรฉ Clermont Auvergne, France
๐Ÿ“˜ Excellence Scholarship in Artificial Intelligence โ€“ Cluster MIAI 2025โ€“2026

๐ŸŽ“ BSc in Life Sciences (Molecular & Computational Biology) โ€” Universitรฉ Clermont Auvergne

๐ŸŽธ Professional Conservatory Studies in Classical Guitar (2015โ€“2021)
๐Ÿพ Veterinary Assistant Diploma (2022โ€“2023)


๐Ÿ”ฌ Research Experience

๐Ÿงซ Bioinformatics Internship โ€“ Oxford Brookes University, Oxford, UK (June-July 2026)

End-to-end in silico drug discovery pipeline targeting Mps1/TTK kinase (PDB: 5LJJ), a mitotic checkpoint regulator overexpressed in aggressive cancers. Built an automated pipeline combining structure-based virtual screening (AutoDock Vina), hinge-region interaction analysis (Gly605/Glu603), ADME/PAINS filtering (RDKit), and a Ridge Regression model (Rยฒ=0.706, LOOCV) trained on physicochemical and structural features to predict binding affinity. Extended to novel candidate discovery via PubChem structural similarity search.

๐Ÿงฉ Bioinformatics Internship โ€“ iGReD, Clermont-Ferrand, France (Feb 2025)

Application of bioinformatics tools to study chromatin structure using 3D bioimaging and structural biology methods.

๐Ÿงฌ Molecular Biology Internship โ€“ iGReD, Clermont-Ferrand, France (June 2025)

Research on regulation mechanisms of transposable elements in Drosophila germline.


๐Ÿ” Research Interests

๐Ÿง  Deep learning applied to biological sequences and protein modeling
๐Ÿ’Š AI-driven drug discovery โ€” molecular docking, ADME filtering, and ML-based binding affinity prediction
๐Ÿงซ Treatement of antibiotic resistant bacterium using AI tools


๐ŸŒ Languages

Language Level
๐Ÿ‡ช๐Ÿ‡ธ Spanish Native
๐Ÿ‡ซ๐Ÿ‡ท French Bilingual
๐Ÿ‡ฌ๐Ÿ‡ง English Fluent (C2 PeopleCert)

๐ŸŽธ Outside the Lab

Iโ€™m also a musician ๐ŸŽถ (classical guitar trained at conservatory), nature lover ๐ŸŒฒ, and sports enthusiast ๐Ÿ.
Youโ€™ll often find me hiking, playing volleyball or padel, and listening to classical music while coding.


๐Ÿ“ซ Letโ€™s Connect!

LinkedIn
๐Ÿ“ง [email protected]
๐Ÿ“ Clermont-Ferrand, France


โญ๏ธ Thanks for stopping by! Iโ€™m always open to collaborations in bioinformatics and AI for life sciences.

Popular repositories Loading

  1. engavilane engavilane Public

    Hello world :)

  2. mps1-drug-discovery mps1-drug-discovery Public

    Open-source in silico drug discovery pipeline targeting Mps1/TTK kinase โ€” virtual screening of 45 known inhibitors + 210 novel candidates, PLIP interaction analysis, ADME filtering, QSAR (Rยฒ=0.73, โ€ฆ

    Python