netcontrol/controllable.txt at master · vrogojin/netcontrol · GitHub

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## This file includes the faster simple heuristics, together with versions of them accounting for the controllable (i.e. drug-targetable) nodes.
##
## Simple, fast heuristics -> see 'simple_fast.txt' for details.
T F 1 (->A)(->T)
T F 1 (->D)(->CA)(->PA)(->N)(->T)
T F 1 (->@CA)(->@PA)(->D)(->CA)(->PA)(->N)(->T)
## Favor controllable nodes and avoid cycles.
T F 1 (->K)(->A)(->T)
## Consider nodes in the following way:
## - driven, indirectly controlled or controllable predecessors of uncontrollable nodes
## - acyclic predecessors of uncontrollable nodes
## - remaining predecessors of uncontrollable nodes
## - a selection of predecessors of controllable nodes (as an alternative to directly marking them driven)
T F 1 (->#XD.#XC.#XK)(->#XA)(->#X)(->#KD.#KC)
T F 1 (->#XD.#XC.#XK)(->#XA)(->#X)(->#KD.#KC.#KP)
T F 1 (->#XD.#XC.#XK)(->#XA)(->#X)(->#KD.#KC.#KP.#KK)
## Same as the above, but include in the first step already seen predecessors of uncontrollable nodes.
T F 1 (->#XD.#XC.#XP.#XK)(->#XA)(->#X)(->#KD.#KC)
T F 1 (->#XD.#XC.#XP.#XK)(->#XA)(->#X)(->#KD.#KC.#KP)
T F 1 (->#XD.#XC.#XP.#XK)(->#XA)(->#X)(->#KD.#KC.#KP.#KK)