@DongdongdongW has reported that COSMIC download sometimes fails to download. Email:
During this process, I encountered some problems. For some reason, the database of COSMIC cannot be downloaded. At the same time, the vcf file from ENSEML is missing in the pipeline. So I chose to download the files from these databases myself and generate the proteogenomics database via pypgatk. When selecting the COSMIC database and cBioportal, I only selected data for cell line A549 and lung cancer type. The size of the database containing the decoy generated by the most popular pypgatk is 3.21GB.
We can add the logic of download using wget and also have an option when the user provides the COSMIC file as a parameter in the pipeline and the pipeline do not need to download it.
@DongdongdongW has reported that COSMIC download sometimes fails to download. Email:
We can add the logic of download using
wgetand also have an option when the user provides the COSMIC file as a parameter in the pipeline and the pipeline do not need to download it.