diff --git a/.changeset/support-apollo-angular-v12.md b/.changeset/support-apollo-angular-v12.md
new file mode 100644
index 0000000000..08324211a1
--- /dev/null
+++ b/.changeset/support-apollo-angular-v12.md
@@ -0,0 +1,7 @@
+---
+"@graphql-codegen/typescript-apollo-angular": patch
+---
+
+Support apollo-angular v12+ combined parameter syntax
+
+For `apolloAngularVersion >= 12`, the generated SDK methods now internally combine variables into the options object when calling apollo-angular methods, matching the v12+ API requirements. The external SDK method signatures remain unchanged for backward compatibility.
diff --git a/packages/plugins/typescript/apollo-angular/src/visitor.ts b/packages/plugins/typescript/apollo-angular/src/visitor.ts
index ba266c0a4d..2e886e69cb 100644
--- a/packages/plugins/typescript/apollo-angular/src/visitor.ts
+++ b/packages/plugins/typescript/apollo-angular/src/visitor.ts
@@ -348,6 +348,8 @@ export class ApolloAngularVisitor extends ClientSideBaseVisitor<
     );
     const hasQueries = this._operationsToInclude.find(o => o.operationType === 'Query');
 
+    const isV12Plus = this.config.apolloAngularVersion >= 12;
+
     const allPossibleActions = this._operationsToInclude
       .map(o => {
         const operationResultType = this._externalImportPrefix + o.operationResultType;
@@ -360,27 +362,40 @@ export class ApolloAngularVisitor extends ClientSideBaseVisitor<
             v => v.type.kind !== Kind.NON_NULL_TYPE || !!v.defaultValue,
           );
 
-        const options =
-          o.operationType === 'Mutation'
+        // For v12+, all OptionsAlone types have <T, V> signature for proper type inference
+        const options = isV12Plus
+          ? `${o.operationType}OptionsAlone<${operationResultType}, ${operationVariablesTypes}>`
+          : o.operationType === 'Mutation'
             ? `${o.operationType}OptionsAlone<${operationResultType}, ${operationVariablesTypes}>`
             : `${o.operationType}OptionsAlone<${operationVariablesTypes}>`;
 
+        // For v12+, combine variables into options when calling apollo-angular
+        const callArgs = isV12Plus ? '{ ...options, variables }' : 'variables, options';
+
         const method = `
 ${camelCase(o.node.name.value)}(variables${
           optionalVariables ? '?' : ''
         }: ${operationVariablesTypes}, options?: ${options}) {
-  return this.${camelCase(o.serviceName)}.${actionType(o.operationType)}(variables, options)
+  return this.${camelCase(o.serviceName)}.${actionType(o.operationType)}(${callArgs})
 }`;
 
         let watchMethod: string;
 
         if (o.operationType === 'Query') {
+          // For v12+, add explicit return type to ensure proper type inference
+          const watchOptions = isV12Plus
+            ? `WatchQueryOptionsAlone<${operationResultType}, ${operationVariablesTypes}>`
+            : `WatchQueryOptionsAlone<${operationVariablesTypes}>`;
+          const returnType = isV12Plus
+            ? `: Apollo.QueryRef<${operationResultType}, ${operationVariablesTypes}>`
+            : '';
+
           watchMethod = `
 
 ${camelCase(o.node.name.value)}Watch(variables${
             optionalVariables ? '?' : ''
-          }: ${operationVariablesTypes}, options?: WatchQueryOptionsAlone<${operationVariablesTypes}>) {
-  return this.${camelCase(o.serviceName)}.watch(variables, options)
+          }: ${operationVariablesTypes}, options?: ${watchOptions})${returnType} {
+  return this.${camelCase(o.serviceName)}.watch(${callArgs})
 }`;
         }
         return [method, watchMethod].join('');
@@ -407,17 +422,29 @@ ${camelCase(o.node.name.value)}Watch(variables${
       hasQueries || hasMutations || hasSubscriptions
         ? `type Omit<T, K extends keyof T> = Pick<T, Exclude<keyof T, K>>;`
         : '';
+
+    // For apollo-angular v12+ with Apollo Client 4, use type aliases with Apollo.Apollo namespace types
+    // (Apollo.Apollo accesses the class namespace from the module import)
+    // Apollo namespace uses <TData, TVariables> order
     const watchType = hasQueries
-      ? `interface WatchQueryOptionsAlone<V> extends Omit<ApolloCore.WatchQueryOptions<V>, 'query' | 'variables'> {}`
+      ? isV12Plus
+        ? `type WatchQueryOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.WatchQueryOptions<T, V>, 'query' | 'variables'>`
+        : `interface WatchQueryOptionsAlone<V> extends Omit<ApolloCore.WatchQueryOptions<V>, 'query' | 'variables'> {}`
       : '';
     const queryType = hasQueries
-      ? `interface QueryOptionsAlone<V> extends Omit<ApolloCore.QueryOptions<V>, 'query' | 'variables'> {}`
+      ? isV12Plus
+        ? `type QueryOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.QueryOptions<T, V>, 'query' | 'variables'>`
+        : `interface QueryOptionsAlone<V> extends Omit<ApolloCore.QueryOptions<V>, 'query' | 'variables'> {}`
       : '';
     const mutationType = hasMutations
-      ? `interface MutationOptionsAlone<T, V> extends Omit<ApolloCore.MutationOptions<T, V>, 'mutation' | 'variables'> {}`
+      ? isV12Plus
+        ? `type MutationOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.MutateOptions<T, V>, 'mutation' | 'variables'>`
+        : `interface MutationOptionsAlone<T, V> extends Omit<ApolloCore.MutationOptions<T, V>, 'mutation' | 'variables'> {}`
       : '';
     const subscriptionType = hasSubscriptions
-      ? `interface SubscriptionOptionsAlone<V> extends Omit<ApolloCore.SubscriptionOptions<V>, 'query' | 'variables'> {}`
+      ? isV12Plus
+        ? `type SubscriptionOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.SubscribeOptions<T, V>, 'query' | 'variables'>`
+        : `interface SubscriptionOptionsAlone<V> extends Omit<ApolloCore.SubscriptionOptions<V>, 'query' | 'variables'> {}`
       : '';
 
     const types = [omitType, watchType, queryType, mutationType, subscriptionType]
diff --git a/packages/plugins/typescript/apollo-angular/tests/apollo-angular.spec.ts b/packages/plugins/typescript/apollo-angular/tests/apollo-angular.spec.ts
index 581e3d7808..1dd99972cb 100644
--- a/packages/plugins/typescript/apollo-angular/tests/apollo-angular.spec.ts
+++ b/packages/plugins/typescript/apollo-angular/tests/apollo-angular.spec.ts
@@ -736,6 +736,152 @@ describe('Apollo Angular', () => {
         export class ApolloAngularSDK {
       `);
     });
+
+    it('should combine variables into options for apolloAngularVersion 12+', async () => {
+      const modifiedSchema = extendSchema(schema, addToSchema);
+      const myFeed = gql(`
+        query MyFeed {
+          feed {
+            id
+          }
+        }
+      `);
+      const docs = [{ location: '', document: myFeed }];
+      const content = (await plugin(
+        modifiedSchema,
+        docs,
+        {
+          sdkClass: true,
+          apolloAngularVersion: 12,
+        },
+        {
+          outputFile: 'graphql.ts',
+        },
+      )) as Types.ComplexPluginOutput;
+
+      // For v12+, use type aliases with Apollo.Apollo namespace types
+      expect(content.content).toBeSimilarStringTo(`
+        type Omit<T, K extends keyof T> = Pick<T, Exclude<keyof T, K>>;
+
+        type WatchQueryOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.WatchQueryOptions<T, V>, 'query' | 'variables'>
+
+        type QueryOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.QueryOptions<T, V>, 'query' | 'variables'>`);
+
+      // For v12+, SDK methods should keep same signature but combine variables into options internally
+      // Watch method should have explicit return type for proper type inference
+      expect(content.content).toBeSimilarStringTo(`
+        myFeed(variables?: MyFeedQueryVariables, options?: QueryOptionsAlone<MyFeedQuery, MyFeedQueryVariables>) {
+          return this.myFeedGql.fetch({ ...options, variables })
+        }
+
+        myFeedWatch(variables?: MyFeedQueryVariables, options?: WatchQueryOptionsAlone<MyFeedQuery, MyFeedQueryVariables>): Apollo.QueryRef<MyFeedQuery, MyFeedQueryVariables> {
+          return this.myFeedGql.watch({ ...options, variables })
+        }
+      `);
+    });
+
+    it('should combine variables into options for mutations with apolloAngularVersion 12+', async () => {
+      const modifiedSchema = extendSchema(schema, addToSchema);
+      const myMutation = gql(`
+        mutation Update($arg: Int) {
+          update(arg: $arg) {
+            id
+          }
+        }
+      `);
+      const docs = [{ location: '', document: myMutation }];
+      const content = (await plugin(
+        modifiedSchema,
+        docs,
+        {
+          sdkClass: true,
+          apolloAngularVersion: 12,
+        },
+        {
+          outputFile: 'graphql.ts',
+        },
+      )) as Types.ComplexPluginOutput;
+
+      // For v12+, use type alias with Apollo.Apollo namespace
+      expect(content.content).toBeSimilarStringTo(`
+        type MutationOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.MutateOptions<T, V>, 'mutation' | 'variables'>`);
+
+      // For v12+, SDK methods should combine variables into options internally
+      expect(content.content).toBeSimilarStringTo(`
+        update(variables?: UpdateMutationVariables, options?: MutationOptionsAlone<UpdateMutation, UpdateMutationVariables>) {
+          return this.updateGql.mutate({ ...options, variables })
+        }
+      `);
+    });
+
+    it('should combine variables into options for subscriptions with apolloAngularVersion 12+', async () => {
+      const modifiedSchema = extendSchema(schema, addToSchema);
+      const mySubscription = gql(`
+        subscription MyFeed {
+          feed {
+            id
+          }
+        }
+      `);
+      const docs = [{ location: '', document: mySubscription }];
+      const content = (await plugin(
+        modifiedSchema,
+        docs,
+        {
+          sdkClass: true,
+          apolloAngularVersion: 12,
+        },
+        {
+          outputFile: 'graphql.ts',
+        },
+      )) as Types.ComplexPluginOutput;
+
+      // For v12+, use type alias with Apollo.Apollo namespace
+      expect(content.content).toBeSimilarStringTo(`
+        type SubscriptionOptionsAlone<T, V extends ApolloCore.OperationVariables> = Omit<Apollo.Apollo.SubscribeOptions<T, V>, 'query' | 'variables'>`);
+
+      // For v12+, SDK methods should combine variables into options internally
+      expect(content.content).toBeSimilarStringTo(`
+        myFeed(variables?: MyFeedSubscriptionVariables, options?: SubscriptionOptionsAlone<MyFeedSubscription, MyFeedSubscriptionVariables>) {
+          return this.myFeedGql.subscribe({ ...options, variables })
+        }
+      `);
+    });
+
+    it('should use legacy call syntax for apolloAngularVersion below 12', async () => {
+      const modifiedSchema = extendSchema(schema, addToSchema);
+      const myFeed = gql(`
+        query MyFeed {
+          feed {
+            id
+          }
+        }
+      `);
+      const docs = [{ location: '', document: myFeed }];
+      const content = (await plugin(
+        modifiedSchema,
+        docs,
+        {
+          sdkClass: true,
+          apolloAngularVersion: 11,
+        },
+        {
+          outputFile: 'graphql.ts',
+        },
+      )) as Types.ComplexPluginOutput;
+
+      // For v11 and below, interfaces should not have OperationVariables constraint
+      expect(content.content).toBeSimilarStringTo(`
+        interface WatchQueryOptionsAlone<V> extends Omit<ApolloCore.WatchQueryOptions<V>, 'query' | 'variables'> {}`);
+      expect(content.content).not.toContain('OperationVariables');
+
+      // For v11 and below, SDK methods should pass variables and options separately
+      expect(content.content).toBeSimilarStringTo(`
+        myFeed(variables?: MyFeedQueryVariables, options?: QueryOptionsAlone<MyFeedQueryVariables>) {
+          return this.myFeedGql.fetch(variables, options)
+        }
+      `);
+    });
   });
 
   describe('near-operation-file', () => {